Abstract
Background: Gastric cancer (GC) is among the most prevalent cancers in both genders, and the survival rate constitutes a measure to evaluate the diagnosis and treatment of GC. Mashhad is a city located in the northern part of Iran where has been identified as a high incidence region for GC. 
Objective: To determine survival rate of GC patients diagnosed in Mashhad and identify whether underling factors including demographic factors, family history, education, addiction and co-morbidities can affect survival rate.
Methods: This cross-sectional study was conducted in two tertiary referral hospitals (Ghaem Hospital and Imamreza Hospital) in Mashhad. Patients were all diagnosed with GC from 2012 to 2016, and their status in 2019 was determined by data collected from the patients’ records in the hospitals and also by phone calls. Kaplan- Meier, Log-Rank test, and Cox Proportional Hazards Model, were used for data analysis using STATA 14.1 software.
Results: Among 308 patients, 230 (74.7%) were male, and 78 (25.3%) were female. The mean of patients’ age and age at diagnosis time were 65.49 and 64.72 years, respectively. Survival proportion at first, third, and fifth year after diagnosis in both sexes using Kaplan-Meier were 0.63, 0.20, and 0.16. Univariate analysis showed that ethnicity (HR=1.58, p=0.034), addiction (HR=0.53, p=0.016), positive family history (HR=1.56, p=0.023), past medical history (HR=7.93, p=0.002) and education level (HR=0.44, p=0.045) had significant effect on survival rate. Multivariate analysis was somehow consistent with those results except for education level. (HR=9.33, p=0.013).
Conclusion: Older age at diagnosis time, male sex, positive family history, coronary artery disease, diabetes mellitus, and hypertension can negatively influence the survival rate of gastric cancer patients, and these could be applied for improving the GC screening and treatment guidelines.
 
Keywords: Mashhad, Proportional Hazards Models, Stomach Neoplasms, Survival Rate

 

» HTML Fulltext    » PDF Fulltext    » doi: 10.19082/7831

The  most recent editorial (June 2021)

Ethics of Publishing Case Reports: Do We Need Ethics Approval and Patient Consent?

An editorial by Dr. Mehrdad Jalalian

Read more.


The worldwide spread of COVID-19 as an emerging, rapidly evolving situation, and the dramatic need of urgent medicine or vaccine, has rapidly brought new hypotheses for pathophysiology and potential medicinal agents to the fore. It is crucial that the research community provide a way to publish this research in a timely manner.

 

To contribute to this important public health discussion, the Electronic Physician Journal is excited to announce a fast-track procedure to help researchers publish their articles on COVID-19 related subjects that fall under the broad definition of public health, internal medicine, and pharmacology. We are especially welcome to all hypotheses about the pathological basis of the COVID-19 infection and the possible characteristics of potential medicine and vaccine. Submit your manuscript here

 


Our previous editorial (June 2020)

Lessons from COVID-19 pandemic and the Morocco’s success story.

An editorial by Dr. Benksim Abdelhafid (Morocco)

Read more.


 

The 6th World Conference on Research Integrity (WCRI) is to be held on June 2-5, 2019 in Hong Kong.

The WCRI is the largest and most significant international conference on research integrity. Since the first conference in Lisbon in 2007, it has given researchers, teachers, funding agencies, government officials, journal editors, senior administrators, and research students opportunities to share experiences and to discuss and promote integrity in research. Read more:


 

TDR Clinical Research and Development Fellowships

Call for applications

Deadline for submission: 7 March 2019, 16:00 (GMT)

TDR provides fellowships for early- to mid-career researchers and clinical trial staff (e.g. clinicians, pharmacists, medical statisticians, data managers, other health researchers) in low- and middle-income countries (LMICs) to learn how to conduct clinical trials. Read more:


Meta-Analysis Workshops in New York, USA, and London, UK, in April and May 2019

Don't miss this exceptional opportunity to learn how to perform and report a Meta-analysis correctly. Two Meta-analysis workshops are organized in April and May 2019 by Dr. Michael Borenstein in New York, USA (April 08-10, 2019) and London, UK (May 27-29).

About the Instructor

Dr. Michael Borenstein, one of the authors of Introduction to Meta-Analysis, is widely recognized for his ability to make statistical concepts accessible to researchers as well as to statisticians. He has lectured widely on meta-analysis, including at the NIH, CDC, and FDA. Read more: